AC Pharmaceuticals

AC pharmaceuticals Pharmaceutical Development Technology Platform

The main use of modern drug development platform in the United States Institute of the United States best modern R & D of new drug delivery technology. This high-tech drugs and will soon become an integral part of the biotechnology industry. 2012, use of drug delivery system for drug sales in the United States will reach 45 billion U.S. dollars, the world reached 65 billion U.S. dollars. Drug delivery system technology can become a hidden reason why such a huge potential for Di industry, one of the reasons yes Xuduojibing Suiranbuduan a new drug is Yanfachulai, Dan Henduo of these drugs in Huoxingchengfen or drugs Benshen Shengwuhuaxue Xing Zhi Zai Tiao Jian Tong Chang Ha and the environment in the human digestive system or circulatory system in the lack of stability, made of commonly used oral dosage forms is difficult. For many proteins and peptides, the existing formulations in effectiveness, toxicity, immunogenicity Deng also many problems, need the appropriate system for the transmission or release of these drugs. There are many existing drugs or even the stability and solubility problems. And when these drugs coming off patent protection expires, many companies are seeking ways to address these issues dominate the market. Drug delivery system is the preferred method of solving these problems.

Transmission of drug release can be applied to a wide range of active ingredients of drugs. From the general non-water-soluble organic compounds, air and light sensitive reagent, to easily digestive protein degradation and peptide drugs can be used as the target application. For many drugs to develop a broader application. U.S. Pharmaceutical R & D drug delivery system includes the following major technology transfer and dosage forms:

1, biodegradable microspheres system.Biodegradable microspheres is a safe and efficient system of drug delivery systems, using FDA approved and widely used in preparation of biodegradable materials. According to performance and delivery requirements of different drugs, drug can be distributed evenly or sub-phase in the microspheres in order to control the concentration of drug in the blood the purpose. Such systems can be designed to run from weeks to months of sustained release formulation. Can choose a variety of anticancer drugs such as drugs, painkillers, etc., for therapeutic purposes while reducing the medication dosage and frequency of drug reduction.

    Second, drugs, pegylated.PEG is a water-soluble polymer, is widely used FDA approved drugs and food additives. PEG modification by protein drugs can increase the water solubility and decrease the immune-derived protein drugs, protein drugs while increasing the stability in vitro and in vivo. Polyethylene glycol can also use other drugs to increase the water-soluble drugs to improve the drug absorption rate, particularly poor water-soluble small molecule drugs, after PEGylation can significantly reduce the drug's side effects, enhance their in vivo circulation time and increase efficiency in the use of the drug.

In addition, we have to prepare different types and different molecular weight polyethylene glycol derivatives technology to adapt to different functional groups modified with the needs of different drugs. Such technology enables the drug have been targeting can further improve the efficiency of drugs and reduce side effects of drug in the body.

   Third, gene vector technology release.We have prepared various types of non-viral gene vector technology. Such carriers can effectively target gene delivery to cells. Compared with viral vectors, non-viral gene vector is a significant advantage of drug side effects, without causing any immune response, can modify the characteristics of target cells and processing.

Fourth, technology and other drugs by micellar solubilization reagents.Micelles and drug solubilization in developing water-soluble drugs with poor application is very important. These reagents with the formation of different complexes of drug, can greatly improve drug solubility and drug absorption efficiency, while reducing drug toxicity, for the preparation and use of pharmaceutical preparations developed a new way. The main application of these techniques: 1, system administration (subcutaneous and intravenous injection); 2, transdermal delivery. In addition, these technologies can have targeting drugs can further improve the efficiency of drugs and reduce side effects of drug in the body.

AC Pharmaceuticals New Products Developed on the Technology Platform

AC pharmaceuticals is using our technology platform, the following drugs were developed, these drugs can achieve in the short term commercialization.

1, anticancer drug taxol preparations

The long-acting release pharmaceutical preparation using advanced technology and have good biocompatibility and biodegradability accessories for preparation of the anticancer drug paclitaxel, reduced the number of injections a week or even once a month. As the local administration, the preparation can improve the paclitaxel on the tumors and lesions of the targeted and targeting greatly improve their efficacy and reduce side effects of existing agents. In addition, this agent can also be used in all patients with cancer during use, such as for use in cancer patients after surgery to prevent the spread of cancer cells, broad range of applications. As preparation production 过程 在 does not Shiyong any auxiliary materials and solvents harmful to the environment, this technology on the environment without adverse effects, so that Zhenzhenglvse Huan Bao.

2, anti-prostate cancer drug and its derivatives LHTRH

The long-acting release pharmaceutical preparation using advanced technology and have good biocompatibility and biodegradability excipients on LHRH and its derivatives for preparation, will be reduced number of injections per month and even every six months. This agent mainly through the administration of the muscle or subcutaneous administration. Avoid the use of the drug operation, while maintaining the dignity of men, but also to avoid the suffering of the patients by the majority of patients of all ages. Because the production process in preparation does not use any of the excipients and solvents harmful to the environment, this same technology on the environment without any adverse effects.

3, polyethylene glycol modified insulin diabetes drugs

The preparation technique using polyethylene glycol modified insulin for insulin to improve the water solubility and enhance its stability, reduce immunogenicity. Because the production process in preparation does not use any of the excipients and solvents harmful to the environment, this technology has no adverse impact on the environment.

4, diabetes, GLP-1 release drug formulations

The long-acting release pharmaceutical preparation using advanced technology and have good biocompatibility and biodegradability excipients on GLP-1 and its derivatives for preparation, number of injections a week to once per month. This agent mainly through the administration of the muscle or subcutaneous administration. Because the production process in preparation does not use any of the excipients and solvents harmful to the environment, this technology has no adverse impact on the environment.

5, anti-hepatitis C drug Ribavirin preparations

The preparation by dry or wet ball technology into a small ball made of Ribavirin and then pressed. This method is high yield, reliable production process can be repetitive. Because the production process in preparation does not use any auxiliary materials harmful to the environment and solvent, this technique has no adverse impact on the environment.

6, the diet drug GLP-4

The long-acting release pharmaceutical preparation using advanced technology and have good biocompatibility and biodegradability excipients on GLP-4 and its derivatives for preparation, number of injections a week to once per month. This agent mainly through the administration of the muscle or subcutaneous administration. Because the production process in preparation does not use any of the excipients and solvents harmful to the environment, this technology has no adverse impact on the environment.

7. Antiallergic (Loratadine, 10mg)

The preparation by direct mixing tablet production method. Process reliable, reproducible.

    8, paracetamol and acetaminophen compound drug (300mg and 500 mg)

The preparation method used straight or mixed wet pressed into a ball further production. Process reliable, reproducible. Moreover, according to application needs, use of the company's technology platform, we can be made into quick release preparation, sustained-release preparations, etc..

9. "Anti-rheumatic bones health" preparations

"Bones health," the main active ingredient preparations, "Bo Shiwei", is the latest high-tech methods from the traditional medicines in the extraction of plant active ingredients. This agent has anti-rheumatic, anti-inflammatory, fever, pain and sedation. Extraction technology advanced, there is no environmental pollution. Skin medication, no toxic side effects.

10. Prostatic effects of pharmaceutical preparations

Prostatic specific medicine is used to prevent health effects treatment of prostatic hyperplasia drugs, raw materials from natural plant extract with a new technology becomes supercritical. No toxic side effects and environmental pollution.

Please feel free to contact us at info@ACPharmaceuticals.comif you have interest in any of the above products.